ABEmax mRNA (m1ψ substitution)
ABEmax mRNA encodes the ABEmax (Adenine Base Editor) protein, a second-generation genome-editing tool for precise adenine-to-guanine (A-to-G) conversions in DNA. Delivered as mRNA, it ensures rapid, high transient expression proportional to mRNA quantity without requiring nuclear uptake. Extensively characterized for its targeting window and off-target effects, ABEmax is ideal for research in gene function, genetic diseases, and therapeutic development.
Croyez’s ABEmax mRNA is produced through in vitro transcription, featuring a Cap1-modified 5' end, a poly(A) tail at the 3' end, and modified nucleotides to reduce immune response. These enhancements ensure stability and performance, allowing the mRNA to function like natural mature mRNAs in cells.
ARTICLE：
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mRNA Length:
5962 nt
Base Composition:
N1-Me-pUTP (N1-mψ)
Concentration:
1.0 mg/ mL
Cap Modification:
Cap 1 structure
Poly A Tail:
Yes
Form:
Liquid
Buffer:
1 mM sodium citrate buffer, pH 6.4.
Storage:
Products can be stored at -80°C or below.
We recommend to aliquot the mRNA solution for a better storage. Avoid repeated freeze/thaw cycles.
Shipping:
The products are shipped on dry ice and should be avoided for freeze-thaw cycles.
Application:
Gene Function Research, Genetic Disease Studies, Therapeutic Development, Genetic Modification
Shipping Conditions:
Dry ice
5962 nt
Base Composition:
N1-Me-pUTP (N1-mψ)
Concentration:
1.0 mg/ mL
Cap Modification:
Cap 1 structure
Poly A Tail:
Yes
Form:
Liquid
Buffer:
1 mM sodium citrate buffer, pH 6.4.
Storage:
Products can be stored at -80°C or below.
We recommend to aliquot the mRNA solution for a better storage. Avoid repeated freeze/thaw cycles.
Shipping:
The products are shipped on dry ice and should be avoided for freeze-thaw cycles.
Application:
Gene Function Research, Genetic Disease Studies, Therapeutic Development, Genetic Modification
Shipping Conditions:
Dry ice
.jpg)
Figure 1.
ABEmax mRNA (m1 ψ substitution) was analyzed on a 2% E-Gel.
Lane 1: Marker,RNA ladder (cat no: CR00004)
Lane 2: ABEmax mRNA (m1 ψ substitution)
.jpg)
Figure 2.
ABEmax mRNA (m1 ψ substitution) was analyzed on a 1% TAE agarose gel at 100 V for 30 minutes.
Lane 1: Marker,RNA ladder (cat no: CR00004).
Lane 2: ABEmax mRNA (m1 ψ substitution)
